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HNRNPK Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23477N-1 50ul / $395
APR23477N-2 100ul / $495
APR23477N-3 200ul / $595

HNRNPK Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23477N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRNPK Polyclonal Antibody.

Molecular Weight

Calculated MW: 48kDa/50kDa/51kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HNRNPK (NP_112552.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Synonyms

HNRNPK; AUKS; CSBP; HNRPK; TUNP; heterogeneous nuclear ribonucleoprotein K

Images

Western blot analysis of extracts of various cell lines, using HNRNPK antibody.

Immunohistochemistry of paraffin-embedded rat liver using HNRNPK Antibody.

Immunohistochemistry of paraffin-embedded human esophagus using HNRNPK Antibody.

Specification

Quantity

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