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ARNT Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23464N-1 50ul / $395
APR23464N-2 100ul / $495
APR23464N-3 200ul / $595

ARNT Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23464N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARNT Polyclonal Antibody.

Molecular Weight

Calculated MW: 84kDa/85kDa/86kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ARNT (NP_001659.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IF

Dilution

IF 1:50 - 1:200

Product Description

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Synonyms

HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2

Images

Immunofluorescence analysis of U-2 OS cells using ARNT antibody.

Specification

Quantity

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