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NAIP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23434N-1 50ul / $395
APR23434N-2 100ul / $495
APR23434N-3 200ul / $595

NAIP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23434N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NAIP Polyclonal Antibody.

Molecular Weight

Calculated MW: _ Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human NAIP (NP_075043.1).

Cross Reactivity

Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Synonyms

NAIP; BIRC1; NLRB1; psiNAIP; NLR family apoptosis inhibitory protein

Images

Western blot analysis of extracts of various cell lines, using NAIP antibody.

Specification

Quantity

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