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CAST Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23361N-1 50ul / $395
APR23361N-2 100ul / $495
APR23361N-3 200ul / $595

CAST Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23361N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAST Polyclonal Antibody.

Molecular Weight

Calculated MW: 63kDa/71- 84kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CAST (NP_001177371.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms

CAST; BS-17; PLACK; calpastatin

Images

Immunohistochemistry of paraffin-embedded human stomach using CAST antibody.

Immunohistochemistry of paraffin-embedded human uterine cancer using CAST antibody.

Specification

Quantity

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