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PAX3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23337N-1 50ul / $395
APR23337N-2 100ul / $495
APR23337N-3 200ul / $595

PAX3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23337N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAX3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/24kDa/44kDa/45kDa/52kDa/53kDa/55kDa Observed MW: 69kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PAX3 (NP_039230.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Synonyms

PAX3; CDHS; HUP2; WS1; WS3; paired box 3

Images

Western blot analysis of extracts of various cell lines, using PAX3 antibody.

Immunofluorescence analysis of MCF-7 cells using PAX3 antibody.

Specification

Quantity

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