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PKM Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23293N-1 50ul / $395
APR23293N-2 100ul / $495
APR23293N-3 200ul / $595

PKM Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23293N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKM Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa/57kDa/58kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PKM (NP_002645.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Synonyms

PKM; CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1; pyruvate kinase PKM

Images

Western blot analysis of extracts of various cell lines, using PKM antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using PKM antibody.

Immunohistochemistry of paraffin-embedded human stomach using PKM antibody.

Specification

Quantity

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