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FBN1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23272N-1 50ul / $395
APR23272N-2 100ul / $495
APR23272N-3 200ul / $595

FBN1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23272N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBN1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 312kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FBN1 (NP_000129.3).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IF

Dilution

IF 1:50 - 1:200

Product Description

This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome.

Synonyms

FBN1; ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFLS; MFS1; OCTD; SGS; SSKS; WMS; WMS2; fibrillin-1

Images

Immunofluorescence analysis of C6 cells using FBN1 Polyclonal Antibody.

Immunofluorescence analysis of NIH-3T3 cells using FBN1 Polyclonal Antibody.

Specification

Quantity

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