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EIF4EBP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23263N-1 50ul / $395
APR23263N-2 100ul / $495
APR23263N-3 200ul / $595

EIF4EBP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23263N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF4EBP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 12kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

A synthetic synthetic peptide of human EIF4EBP1 (NP_004086.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Synonyms

EIF4EBP1; 4E-BP1; 4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1

Images

Immunohistochemistry of paraffin-embedded human breast cancer using EIF4EBP1 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using EIF4EBP1 antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using EIF4EBP1 antibody.

Specification

Quantity

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