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SELENOM Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23256N-1 50ul / $395
APR23256N-2 100ul / $495
APR23256N-3 200ul / $595

SELENOM Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23256N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SELENOM Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa Observed MW: 16kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SELENOM (NP_536355.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Synonyms

SELENOM; SELM; SEPM; selenoprotein M

Images

Western blot analysis of extracts of various cell lines, using SELENOM antibody.

Specification

Quantity

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