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ERVW-1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23117N-1 50ul / $395
APR23117N-2 100ul / $495
APR23117N-3 200ul / $595

ERVW-1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23117N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ERVW-1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 59kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human ERVW-1 (NP_001124397.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Synonyms

ERVW-1; ENV; ENVW; ERVWE1; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV; syncytin-1

Images

Western blot analysis of extracts of various cell lines, using ERVW-1 antibody.

Specification

Quantity

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