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IL7 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR23093N-1 50ul / $395
APR23093N-2 100ul / $495
APR23093N-3 200ul / $595

IL7 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR23093N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL7 Polyclonal Antibody.

Molecular Weight

Calculated MW: 7kDa/15kDa/20kDa Observed MW: 33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL7 (NP_000871.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Synonyms

IL7; IL-7; interleukin-7

Images

Western blot analysis of extracts of various cell lines, using IL7 antibody.

Immunohistochemistry of paraffin-embedded rat liver using IL7 antibody.

Immunohistochemistry of paraffin-embedded mouse liver using IL7 antibody.

Specification

Quantity

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