> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CHRNA4 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR23072N |
Product Type |
Polyclonal Antibodies | Field of Research |
Neuroscience>Neurodegenerative Diseases |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CHRNA4 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
60kDa/69kDa
Observed MW:
70kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant protein of human CHRNA4
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Cross Reactivity |
Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.
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Synonyms |
CHRNA4; BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4; cholinergic receptor nicotinic alpha 4 subunit
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Images |
Western blot analysis of extracts of mouse kidney, using CHRNA4 antibody. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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