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E2F2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22953N-1 50ul / $395
APR22953N-2 100ul / $495
APR22953N-3 200ul / $595

E2F2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22953N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>ErbB-HER Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality E2F2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 47kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic synthetic peptide of human E2F2 (NP_004082.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1.

Synonyms

E2F2; E2F-2; transcription factor E2F2

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Specification

Quantity

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