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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] XPA Polyclonal Antibody

[KO Validated] XPA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22852N-1 50ul / $395
APR22852N-2 100ul / $495
APR22852N-3 200ul / $595

[KO Validated] XPA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22852N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] XPA Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human XPA (NP_000371.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

Synonyms

XPA; XP1; XPAC; DNA repair protein complementing XP-A cells

Images

Western blot analysis of extracts of various cell lines, using XPA antibody.

Western blot analysis of extracts from normal (control) and XPA knockout (KO) HeLa cells, using XPA antibody.

Immunofluorescence analysis of GFP-RNF168 transgenic U2OS cells using XPA antibody.

Specification

Quantity

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