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LATS2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22843N-1 50ul / $395
APR22843N-2 100ul / $495
APR22843N-3 200ul / $595

LATS2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22843N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LATS2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 120kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human LATS2 (NP_055387.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Synonyms

LATS2; KPM; large tumor suppressor kinase 2

Images

Western blot analysis of extracts of various cell lines, using LATS2 antibody.

Specification

Quantity

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