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TFPI Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22833N-1 50ul / $395
APR22833N-2 100ul / $495
APR22833N-3 200ul / $595

TFPI Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22833N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TFPI Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa/35kDa Observed MW: 31kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TFPI (NP_001027452.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Synonyms

TFPI; EPI; LACI; TFI; TFPI1; tissue factor pathway inhibitor

Images

Western blot analysis of extracts of various cell lines, using TFPI antibody.

Immunofluorescence analysis of MCF-7 cells using TFPI antibody.

Specification

Quantity

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