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PVRL4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22737N-1 50ul / $395
APR22737N-2 100ul / $495
APR22737N-3 200ul / $595

PVRL4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22737N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PVRL4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa/55kDa Observed MW: 55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PVRL4 (NP_112178.2).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Synonyms

NECTIN4; EDSS1; LNIR; PRR4; PVRL4; nectin-4

Images

Western blot analysis of extracts of various cell lines, using PVRL4 antibody.

Specification

Quantity

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