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CEP290 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22735N-1 50ul / $395
APR22735N-2 100ul / $495
APR22735N-3 200ul / $595

CEP290 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22735N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CEP290 Polyclonal Antibody.

Molecular Weight

Calculated MW: 180kDa/290kDa Observed MW: 290kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CEP290 (NP_079390.3).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Synonyms

CEP290; 3H11Ag; BBS14; CT87; JBTS5; LCA10; MKS4; NPHP6; POC3; SLSN6; rd16; centrosomal protein 290

Images

Western blot analysis of extracts of various cell lines, using CEP290 antibody.

Specification

Quantity

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