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CCDC88A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22719N-1 50ul / $395
APR22719N-2 100ul / $495
APR22719N-3 200ul / $595

CCDC88A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22719N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCDC88A Polyclonal Antibody.

Molecular Weight

Calculated MW: 207kDa/212kDa/215kDa/216kDa Observed MW: 220kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CCDC88A (NP_001129069.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

CCDC88A; APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO; girdin

Images

Western blot analysis of extracts of various cell lines, using CCDC88A antibody.

Specification

Quantity

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