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LILRB3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22689N-1 50ul / $395
APR22689N-2 100ul / $495
APR22689N-3 200ul / $595

LILRB3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22689N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>B Cell Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LILRB3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 69kDa/71kDa Observed MW: 69kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human LILRB3 (NP_001307889.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

LILRB3; CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIR-B; PIRB; leukocyte immunoglobulin like receptor B3

Images

Western blot analysis of extracts of Jurkat cells, using LILRB3 antibody.

Specification

Quantity

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