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RARB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22615N-1 50ul / $395
APR22615N-2 100ul / $495
APR22615N-3 200ul / $595

RARB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22615N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Nuclear Receptor Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RARB Polyclonal Antibody.

Molecular Weight

Calculated MW: 37kDa/50kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human RARB

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.

Synonyms

RARB; HAP; MCOPS12; NR1B2; RARbeta1; RRB2; retinoic acid receptor beta

Images

Western blot analysis of extracts of various cell lines, using RARB Antibody.

Immunohistochemistry of paraffin-embedded rat kidney using RARB antibody.

Immunofluorescence analysis of U2OS cells using RARB antibody.

Specification

Quantity

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