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ADD1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22509N-1 50ul / $395
APR22509N-2 100ul / $495
APR22509N-3 200ul / $595

ADD1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22509N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADD1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa/69kDa/73kDa/80kDa/84kDa Observed MW: 73kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ADD1 (NP_054908.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Synonyms

ADD1; ADDA; adducin 1

Images

Western blot analysis of extracts of various cell lines, using ADD1 antibody.

Specification

Quantity

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