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TIMP2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR22149N-1 50ul / $395
APR22149N-2 100ul / $495
APR22149N-3 200ul / $595

TIMP2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR22149N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIMP2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human TIMP2 (NP_003246.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Synonyms

TIMP2; CSC-21K; DDC8; metalloproteinase inhibitor 2

Images

Western blot analysis of extracts of various cell lines, using TIMP2 antibody.

Immunofluorescence analysis of MCF-7 cells using TIMP2 antibody.

Specification

Quantity

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