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CASR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20807N-1 50ul / $395
APR20807N-2 100ul / $495
APR20807N-3 200ul / $595

CASR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20807N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASR Polyclonal Antibody.

Molecular Weight

Calculated MW: 120kDa/121kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CASR (NP_001171536.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

Synonyms

CASR; CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR; calcium sensing receptor

Images

Western blot analysis of extracts of various cell lines, using CASR antibody.

Specification

Quantity

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