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RTKN Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19940N-1 50ul / $395
APR19940N-2 100ul / $495
APR19940N-3 200ul / $595

RTKN Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19940N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RTKN Polyclonal Antibody.

Molecular Weight

Calculated MW: 56kDa/61kDa/62kDa Observed MW: 63kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RTKN (NP_001015056.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

RTKN; rhotekin

Images

Western blot analysis of extracts of various cell lines, using RTKN antibody.

Immunofluorescence analysis of MCF-7 cells using RTKN antibody.

Specification

Quantity

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