> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MDM2 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR19917N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Cell Cycle |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MDM2 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
11-14kDa/24-55kDa
Observed MW:
52kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human MDM2 (NP_002383.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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Synonyms |
MDM2; ACTFS; HDMX; hdm2; MDM2 proto-oncogene
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Images |
Western blot analysis of extracts of various cell lines, using MDM2 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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