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IL12RB1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19911N-1 50ul / $395
APR19911N-2 100ul / $495
APR19911N-3 200ul / $595

IL12RB1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19911N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL12RB1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 42kDa/72kDa/73kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL12RB1 (NP_714912.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.

Synonyms

IL12RB1; CD212; IL-12R-BETA1; IL12RB; IMD30; interleukin-12 receptor subunit beta-1

Images

Immunohistochemistry of paraffin-embedded rat kidney using IL12RB1 antibody.

Immunofluorescence analysis of MCF7 cells using IL12RB1 antibody.

Specification

Quantity

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