> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > IL12RB1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR19911N |
Product Type |
Polyclonal Antibodies | Field of Research |
Immunology & Inflammation>CDs |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL12RB1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
42kDa/72kDa/73kDa
Observed MW:
_
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human IL12RB1 (NP_714912.1).
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Cross Reactivity |
Human,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
IHC,IF
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Dilution |
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
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Synonyms |
IL12RB1; CD212; IL-12R-BETA1; IL12RB; IMD30; interleukin-12 receptor subunit beta-1
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Images |
Immunohistochemistry of paraffin-embedded rat kidney using IL12RB1 antibody.
Immunofluorescence analysis of MCF7 cells using IL12RB1 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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