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DR1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19891N-1 50ul / $395
APR19891N-2 100ul / $495
APR19891N-3 200ul / $595

DR1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19891N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DR1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 19kDa Observed MW: 19kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DR1 (NP_001929.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Synonyms

DR1; NC2; NC2-BETA; NC2B; NCB2; protein Dr1

Images

Western blot analysis of extracts of mouse spleen, using DR1 antibody.

Immunohistochemistry of paraffin-embedded human gastric cancer using DR1 antibody.

Immunofluorescence analysis of MCF7 cells using DR1 antibody.

Specification

Quantity

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