> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BAK1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR19876N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Apoptosis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAK1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
16kDa/23kDa
Observed MW:
26kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic peptide of human BAK1 (NP_001179.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
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Product Description |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
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Synonyms |
BAK1; BAK; BAK-LIKE; BCL2L7; CDN1; BCL2 antagonist/killer 1
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Images |
Western blot analysis of extracts of MCF7 cells, using BAK1 Antibody.
Immunohistochemistry of paraffin-embedded human kidney cancer using BAK1 antibody.
Immunohistochemistry of paraffin-embedded human stomach cancer using BAK1 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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