> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AMPK alpha 1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR18939N |
Product Type |
Polyclonal Antibodies | Field of Research |
Endocrine & Metabolism>AMPK Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMPK alpha 1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
64kDa/65kDa
Observed MW:
65kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human AMPK alpha 1 (NP_006242.5).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
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Product Description |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Synonyms |
PRKAA1; AMPK; AMPKa1; protein kinase AMP-activated catalytic subunit alpha 1
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Images |
Western blot analysis of extracts of various cell lines, using PRKAA1 antibody.
Immunofluorescence analysis of HeLa cells using AMPK alpha 1 antibody. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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