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DSC2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17831N-1 50ul / $395
APR17831N-2 100ul / $495
APR17831N-3 200ul / $595

DSC2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17831N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DSC2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 93kDa/99kDa Observed MW: 100kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DSC2 (NP_077740.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:2000

Product Description

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Synonyms

DSC2; ARVD11; CDHF2; DG2; DGII/III; DSC3; desmocollin-2

Images

Western blot analysis of extracts of various cell lines, using DSC2 antibody.

Specification

Quantity

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