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CDH12 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17825N-1 50ul / $395
APR17825N-2 100ul / $495
APR17825N-3 200ul / $595

CDH12 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17825N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH12 Polyclonal Antibody.

Molecular Weight

Calculated MW: 84kDa/88kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CDH12 (NP_004052.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:2000

Product Description

This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.

Synonyms

CDH12; CDHB; cadherin-12

Images

Western blot analysis of extracts of various cell lines, using CDH12 antibody.

Specification

Quantity

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