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PTPRJ Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17798N-1 50ul / $395
APR17798N-2 100ul / $495
APR17798N-3 200ul / $595

PTPRJ Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17798N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPRJ Polyclonal Antibody.

Molecular Weight

Calculated MW: 57kDa/145kDa Observed MW: 260kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PTPRJ (NP_002834.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:1000

Product Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

PTPRJ; CD148; DEP1; HPTPeta; R-PTP-ETA; SCC1; protein tyrosine phosphatase, receptor type J

Images

Western blot analysis of extracts of Raji cells, using PTPRJ antibody.

Specification

Quantity

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