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CRLF2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17784N-1 50ul / $395
APR17784N-2 100ul / $495
APR17784N-3 200ul / $595

CRLF2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17784N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRLF2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 26kDa/29kDa/42kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CRLF2 (NP_071431.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:1000

Product Description

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Synonyms

CRLF2; CRL2; CRLF2Y; TSLPR; cytokine receptor-like factor 2

Images

Western blot analysis of extracts of various cell lines, using CRLF2 antibody.

Specification

Quantity

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