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ATP2B4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17733N-1 50ul / $395
APR17733N-2 100ul / $495
APR17733N-3 200ul / $595

ATP2B4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17733N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP2B4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 124-137kDa Observed MW: 138kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ATP2B4 (NP_001675.3).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:4000

Product Description

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

ATP2B4; ATP2B2; MXRA1; PMCA4; PMCA4b; PMCA4x; ATPase plasma membrane Ca2+ transporting 4

Images

Western blot analysis of extracts of mouse brain, using ATP2B4 antibody.

Specification

Quantity

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