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CaVgamma2 Antibody

Catalog # Availability Size / Price Inquiry
APR15279G 50 μl / $695

CaVgamma2 Antibody

Brand

Leading Biology

Catalog Number

APR15279G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CaVgamma2 antibody.

Molecular Weight

35895 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Peptide (C)RATDYLQASAITRIPS, corresponding to amino acid residues 213-228 of mouse Cav??2 (Accession O88602). Intracellular, C-terminus.

GeneID

UniProt ID

Summary

Theγ subunit protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. γ1 was first identified in skeletal muscle as a part of the proteins complex purified as the DHP receptor.Eight γ subunit isoforms were identified in mammalian genoms and they share some sequence as well as structure homology.1 γ subunit contains four transmembrane helixes, with intracellular N and C termini. Usually their association with the pore-forming α1 subunit results in reduced current amplitude.CaVγ2 isalso known as stargazin, and interacts and regulates the activityand trafficking ofAMPA glutamate receptors.2

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:200-1:2000

Synonyms

Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin, Transmembrane AMPAR regulatory protein gamma-2, TARP gamma-2, Cacng2, Stg

Images

Western blot analysis of rat brain membranes: 1. Anti-Ca γ2 antibody ( APR15279G), (1:200). 2. Anti-Ca γ2 antibody, preincubated with the control peptide antigen.

Specification

Quantity

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