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KV7.5 Antibody

Catalog # Availability Size / Price Inquiry
AMM06249G 50 μl / $695

KV7.5 Antibody

Brand

Leading Biology

Catalog Number

AMM06249G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KV7.5 antibody.

Molecular Weight

102258 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Peptide (C)RGSQDFYPKWRESK, corresponding to amino acid residues 856-869 of mouse Kv7.5 (Accession Q9JK45). Intracellular, C-terminus.

GeneID

UniProt ID

Summary

KCNQ genes encode members of the KV7 K+ channels. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. Five members belong to this family (KV7.1-KV7.5) of which KV7.2 to KV7.5 are expressed in the nervous system1-3. KV7.5 is also expressed in visceral smooth muscle4 and skeletal muscle5.These channels form subunits of the low threshold voltage gated K+ channel. KV7.2 and KV7.3 mostly form heteromers to form the M current. KV7.5 is known to contribute to this current1.

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:200-1:2000 IHC~~1:100

Synonyms

Potassium voltage-gated channel subfamily KQT member 5, KQT-like 5, Potassium channel subunit alpha KvLQT5, Voltage-gated potassium channel subunit Kv75, Kcnq5

Images

Western blot analysis of rat hippocampus lysate (lanes 1 and 4), mouse brain lysate (lanes 2 and 5) an rat brain lysate (lanes 3 and 6): 1-3. Anti- K 7.5 antibody ( AMM06249G), (1:200). 4-5. Anti-K 7.5 antibody, preincubated with the control peptide antigen.

Expression of K 7.5 in rat hippocampus Immunohistochemical staining of immersion-fixed, free floating rat brain frozen sections using Anti-K 7.5 antibody ( AMM06249G), (1:100). A. K 7.5 (green) is expressed in hilar cells of the hippocampal dentate gyrus. B. Double-staining of K 7.5 (green) with a neuronal marker (“Milli-Mark” from Millipore, red) reveals partial localization with hilar interneurons (arrow points at an example).

Specification

Quantity

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