> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SNCA AntibodyBrand |
Leading Biology | Catalog Number |
APR13427G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SNCA antibody.
|
||
Molecular Weight |
Predicted: 12 kDa Observed: 16 kDa
|
||
Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human, Mouse, Rat
|
||
Target |
SNCA; SNCA antibody is human, mouse and rat reactive. At least three isoforms of SNCA are known to exist.
|
||
Isotype |
IgG
|
||
Symbol |
NACP, PARK1
|
||
GeneID |
|||
UniProt ID |
|||
Function |
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
|
||
Summary |
Alpha-Synuclein (SNCA) is a hallmark of Alzheimer’s disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson’s disease (4,5).
|
||
Form |
Liquid |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, IHC-P, IF, E
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
