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ME1 Antibody

Catalog # Availability Size / Price Inquiry
APR08406G 0.1 mg / $695

ME1 Antibody

Brand

Leading Biology

Catalog Number

APR08406G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ME1 antibody.

Molecular Weight

Predicted: 63 kDa Observed: 63 kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

ME1; ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.

Isotype

IgG

GeneID

UniProt ID

Summary

ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1). ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2). It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3). The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4). ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Images

Western blot analysis of ME1 in 293 cell lysate with ME1 antibody at 1 μg/ml.

Immunohistochemistry of ME1 in mouse liver tissue with ME1 antibody at 5 μg/mL.

Specification

Quantity

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