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Nucleobindin-2 Antibody

Catalog # Availability Size / Price Inquiry
APR17618G 0.1 mg / $695

Nucleobindin-2 Antibody

Brand

Leading Biology

Catalog Number

APR17618G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Nucleobindin-2 antibody.

Molecular Weight

Predicted: 46 kDa Observed: 54 kDa

Cellular Localization

Antigen Cellular Localization: Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

NUCB2; Nucleobindin-2 antibody is predicted to not cross-react with NUCB1.

Isotype

IgG

Symbol

NEFA

GeneID

UniProt ID

Function

Calcium-binding protein. May have a role in calcium homeostasis.

Summary

Nucleobindin-2 Antibody: NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of Nucleobindin-2 in rat brain tissue lysate with Nucleobindin-2 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 2.5 μg/ml.

Immunofluorescence of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 20 μg/ml.

Specification

Quantity

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