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RUSC2 Antibody

Catalog # Availability Size / Price Inquiry
AMM07698G 0.1 mg / $695

RUSC2 Antibody

Brand

Leading Biology

Catalog Number

AMM07698G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RUSC2 antibody.

Molecular Weight

161225 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol. Note=Cytosolic punctate distribution. Also observed in the perinuclear region

Host

Rabbit

Species Reactivity

Human, Mouse

Target

RUSC2; At least three isoforms are known to exist; this antibody will detect all three isoforms. This antibody is predicted to not cross-react with RUSC1.

Isotype

IgG

Symbol

KIAA0375

GeneID

UniProt ID

Summary

RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of RUSC2 in SK-N-SH cell lysate with RUSC2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Immunohistochemistry of RUSC2 in human brain tissue with RUSC2 antibody at 5 μg/mL.

Immunofluorescence of RUSC2 in human brain tissue with RUSC2 antibody at 20 μg/mL.

Specification

Quantity

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