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SIK3 Antibody

Catalog # Availability Size / Price Inquiry
AMM07802G 0.1 mg / $695

SIK3 Antibody

Brand

Leading Biology

Catalog Number

AMM07802G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SIK3 antibody.

Molecular Weight

139980 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Note=Locates to punctate structures within the cytoplasm on binding to YWHAZ

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Target

SIK3; At least three isoforms of SIK3 are known to exist; this antibody will detect two isoforms. SIK3 antibody is predicted to not cross-react with SIK1 and SIK2.

Isotype

IgY

Symbol

KIAA0999, QSK

GeneID

UniProt ID

Summary

SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Images

Western blot analysis of SIK3 in rat brain tissue lysate with SIK3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunofluorescence of SIK3 in rat brain cells with SIK3 antibody at 20 μg/mL.

Specification

Quantity

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