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Paralemmin3 Antibody

Catalog # Availability Size / Price Inquiry
APR17755G 0.1 mg / $695

Paralemmin3 Antibody

Brand

Leading Biology

Catalog Number

APR17755G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Paralemmin3 antibody.

Molecular Weight

71695 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane; Lipid-anchor

Host

Rabbit

Species Reactivity

Human

Target

PALM3; At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform

Isotype

IgG

GeneID

UniProt ID

Function

ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling.

Summary

Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of Paralemmin3 in MCF7 cell lysate with Paralemmin3 antibody at 1 μg/mL.

Immunocytochemistry of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 5 μg/mL.

Immunofluorescence of Paralemmin 3 in MCF7 cells with Paralemmin 3 antibody at 20 μg/mL.

Specification

Quantity

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