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ZIP10 Antibody

Catalog # Availability Size / Price Inquiry
APR10786G 0.1 mg / $695

ZIP10 Antibody

Brand

Leading Biology

Catalog Number

APR10786G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZIP10 antibody.

Molecular Weight

94132 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

Slc39a10;

Isotype

IgG

Symbol

KIAA1265, ZIP10

GeneID

UniProt ID

Function

May act as a zinc-influx transporter.

Summary

ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of ZIP10 in human spleen tissue lysate with ZIP10 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of ZIP10 in human spleen tissue with ZIP10 antibody at 2.5 μg/mL.

Immunofluorescence of ZIP10 in human spleen tissue with ZIP10 antibody at 20 μg/mL.

Specification

Quantity

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