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SYNPO2L Antibody

Catalog # Availability Size / Price Inquiry
AMM08071G 0.1 mg / $695

SYNPO2L Antibody

Brand

Leading Biology

Catalog Number

AMM08071G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SYNPO2L antibody.

Molecular Weight

102481 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

SYNPO2L;

Isotype

IgG

GeneID

UniProt ID

Function

Actin-associated protein that may play a role in modulating actin-based shape.

Summary

SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 μg/mL.

Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 μg/mL.

Specification

Quantity

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