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LMBRD1 Antibody

Catalog # Availability Size / Price Inquiry
APR08252G 0.1 mg / $695

LMBRD1 Antibody

Brand

Leading Biology

Catalog Number

APR08252G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LMBRD1 antibody.

Molecular Weight

61389 Da

Cellular Localization

Antigen Cellular Localization: Lysosome membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

LMBRD1;

Isotype

IgG

Symbol

C6orf209, NESI

GeneID

UniProt ID

Function

Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV).

Summary

LMBRD1 Antibody: LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of LMBRD1 in human brain tissue lysate with LMBRD1 antibody at 1 μg/mL.

Immunohistochemistry of LMBRD1 in human brain tissue with LMBRD1 antibody at 2.5 μg/mL.

Immunofluorescence of LMBRD1 in human brain tissue with LMBRD1 antibody at 20 μg/mL.

Specification

Quantity

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