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ATG9B Antibody

Catalog # Availability Size / Price Inquiry
APG02068G 0.1 mg / $695

ATG9B Antibody

Brand

Leading Biology

Catalog Number

APG02068G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG9B antibody.

Molecular Weight

101019 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1 and ATG13

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

ATG9B;

Isotype

IgG

Symbol

APG9L2, NOS3AS

GeneID

UniProt ID

Function

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).

Summary

ATG9B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, ICC, E

Images

Western blot analysis of ATG9B in HeLa cell lysate with ATG9B antibody at (A) 1 and (B) 2 μg/mL.

Immunocytochemistry of ATG9B in HeLa cells with ATG9B antibody at 10 μg/mL.

Immunofluorescence of ATG9B in Hela cells with ATG9B antibody at 20 μg/mL.

Specification

Quantity

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