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PLEKHM2 Antibody

Catalog # Availability Size / Price Inquiry
APR11165G 0.1 mg / $695

PLEKHM2 Antibody

Brand

Leading Biology

Catalog Number

APR11165G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLEKHM2 antibody.

Molecular Weight

112780 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

PLEKHM2;

Isotype

IgG

Symbol

KIAA0842, SKIP

GeneID

UniProt ID

Function

May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation.

Summary

PLEKHM2 Antibody: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of PLEKHM2 in rat brain tissue lysate with PLEKHM2 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of PLEKHM2 in human liver tissue with FAM59A antibody at 5 μg/mL.

Immunofluorescence of PLEKHM2 in Human Brain cells with PLEKHM2 antibody at 20 μg/mL.

Specification

Quantity

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