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Transthyretin Antibody

Catalog # Availability Size / Price Inquiry
APR13797G 0.1 mg / $695

Transthyretin Antibody

Brand

Leading Biology

Catalog Number

APR13797G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Transthyretin antibody.

Molecular Weight

Predicted: 16 kDa Observed: 18 kDa

Cellular Localization

Antigen Cellular Localization: Secreted. Cytoplasm.

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Target

TTR;

Isotype

IgY

Symbol

PALB

GeneID

UniProt ID

Function

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Summary

Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of Transthyretin in HepG2 cell lysate with Transthyretin antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of Transthyretin in human lung tissue with Transthyretin antibody at 2.5 μg/mL.

Immunofluorescence of Transthyretin in human lung tissue with Transthyretin antibody at 20 μg/mL.

Specification

Quantity

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