> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RGP1 AntibodyBrand |
Leading Biology | Catalog Number |
AMM07572G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RGP1 antibody.
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Molecular Weight |
42455 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytosol. Membrane
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
RGP1;
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Isotype |
IgG
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Symbol |
KIAA0258
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GeneID |
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UniProt ID |
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Function |
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors.
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Summary |
RGP1 Antibody: Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, a protein that forms a tight complex with RIC1. This complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 is localized to the Golgi and is thought to be a potential Golgi recycling factor. Rgp1 yeast mutants exhibit defects in retrograde trafficking similar to those seen in yeast with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells to that seen in yeast.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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